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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5ef7d34368f31205d28721e6114b7baac5104cca44b173b9f4d35d80d07872' 
  AND token = 'tFFUlO+hMyblA7n7Br+onS4dMraSJmcuzwB1MpT0thY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}