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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8554238462ffa6dd863c400cf02be99150c8ec1b1227c340f8d786e4b47f46e0' 
  AND token = 'W2FyKGghBl0nxWAoUsFPaI5p8lPJvlfwpUdSbtMxHvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}