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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f113726940eb5ad46e453577da0397ef1d2418635498b42714da0ad95815970' 
  AND token = 'IIbemSmb++e9t7H+HbFKEbWtq+sq4oYB5d+cfWMAxEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}