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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e461cd3969f1b69c42a94c0696bd3e59047999ee0035b80777f7e010c453ce81' 
  AND token = 'UzKGXK7+Lkkb/RaaNe6BoAZCPJ300DfUL6AZwp5LBO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}