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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e537181e4b57ee34639fef30212b532f46720fb37f29ef895604982b9f43ce9c' 
  AND token = 'QWXNvZUKROeM/Q42UJ6ATdbsewce0ThfG99YAiDIWA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}