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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c34eac9f8dafd3463d801a64cb21b2165dd7cb9f78a51bd5f682a8e7a34bff53' 
  AND token = 'P8VAqxOH/EMlEmL+xFyPvMIC9fPbb32QEYZJLnkaMO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}