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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5240b0b78a5f053e90e9d8135bb28595b37f597ca7e107c4623196d0c7c6a46' 
  AND token = 'IiWZtYpjeOeBpMapnT/VsV435+fUFiw2t08kESn+7Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}