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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bff085052ecdbeed9050b837967998b7b69326cc8da183f6a94274210303056' 
  AND token = 'MYbVtyuKl66xLEudw1FJneczX9+12C943b3VKVfRQ7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}