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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c1645b6718a0f59fd989df3ae690eba0ebdf9efb72160228368a68819c27f0' 
  AND token = '3n5Ye1Vr9P9tVCzTXiyXNpZOt4YGYw5mX9MgFu2J+3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}