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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b743bf0326ea2ecd361a080aeb04b2919775f879ad4a68af4e9d68a57d006d9' 
  AND token = '6HVEeQOM6iS11CgrQ5rb+T12ZtEeWLSaw16f1hf66Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}