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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1aab918627d2aabba5eeb80b1bdcdc9a34352b30ed0f0cb8b0f78049b76473' 
  AND token = 'S88nbQYpTI91dOqxVThOkA4l1QwxuP4yokfcGgSKhpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}