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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19d9c53c5afb30f7440a6c4c8bf676d1d3ec08306859eb4cc3d90658d74540d' 
  AND token = 'EgJ1X87jRQdg4tUSUV5HwQ3aGXYcaMUmNfGLTAZXTXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}