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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ab86f9ec60b6c6edf2231e0f165d480c440f3b7c4964ebfb7f0c3bd6b02685' 
  AND token = '1lSgK8ucZdi8Vn8r/sG3wKgDiPIcIuGrpNMxV4dmmOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}