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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '564a9e1205811f26087b08676465860ea868c20af329d93ac063e6e955d36f5a' 
  AND token = 'GSdtYTFCz0himXWDhgmQZP4e7cdBYcyNdvvDa2ZIW9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}