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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c90ed697e3fcd635e7480ca3a8e37c200de00dcb27bb863ca7bdd04e70e8398' 
  AND token = 'ym/S2udcvKm8OSasCZj+pkPPhAxiFcaOwON4qDKj/mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}