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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d8c3268ca66acd235fd0cb352548ece81a89530f90cac1d66a18739c20fcad' 
  AND token = 'lHap9ub0sxqTAo8y3UFbNs7NisItNJgwBJCIhurzxrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}