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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a27cd71b35570de9c1a66840dfbad92e195d2784aace613df01002ff96fcf0' 
  AND token = 'f3P3oWc9F4Nzxseq055YS9+Fv6U0SsMbZvrISXfmcq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}