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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527e551d7145c1fa5a66f3f1fc5bdfcc503b3b693eac76eb3f28e144d0a1c414' 
  AND token = '6vfjn0zNzqQAfSXirKs5u9NLKE03sOClQ6V3Wl2G2jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}