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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2457dad665ad296215edce72644185a3400fdbaa56c2e49d7fd223d3438df29f' 
  AND token = 'Dj2JETcWqf+a7RUdP9+nVv2gVtPB8/MJfRn8DZSLP6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}