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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0a4de987a45233e70f703ffcc5b202e1f3dc7366b438199b53ed3689ae51dc' 
  AND token = '9rPBF0BBqduDq5ZeMge3RDPjo8Djmhr4Yt9AB/eKMSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}