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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25384eb1255b747d25710529332ca33f4876e09836a1f3c67ac80108bbe165d' 
  AND token = '4EguC62YO8vvoh08uExRUh1WXjlmXcxnV7keXPec+Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}