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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0987b3a13b9383e510df575b9eaa36a71a2a8e11c6e687b2a7bcbb11547bbb' 
  AND token = 'nWFQ5k5u52fsJhhxy+8Na9rNUfOHLwySbHc0MRCapW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}