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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e403289cf262ebf30e685b34765b91431165545a1c535b4458e5ec444c0605' 
  AND token = '7j6+MJ93/MS2VDWzAWki3yr675//I0FNQuReM83WlpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}