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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180ba223534a8baea9adfbbe3bc0bf9ae91c10465f96e29d27c6a79146e69354' 
  AND token = 'SXUKvOdHRgrt3w1Hsxs6/nj58z4f9w2VM3v4dRS7DHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}