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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e2d277a244860375dc3d6dcedcaed7a212254205010ed353c941ece3d21f063' 
  AND token = '0Vpp5RuYSEiV+FwU8RqOye0z06v405fa9Gn5R+CBUiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}