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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226c295f6b7899409c37bb63b3dcccda42ed682570b8564428dac38de160064f' 
  AND token = 'y6ioxOp9ffuSELzipkvwFHlGYUOIQZ4grMp36TD3vlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}