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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede4c743efad404cf1df72379fdc449ac70313adf6fdb394285e960c59811850' 
  AND token = 'zs7hrSRNU4oeDlNXDaVc9Q2wyryFu7xwf3EbJFaNxNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}