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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5124145872c76e3263c7dc73d5b94b9390d9b21b2630bef1d92d2e50383a26b5' 
  AND token = 'kjnuqc0HYnQXPWn/GKAlxgL57WsEYb82xiBDP8AtXR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}