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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7437a3849327391046d0e9fc64d55da9fe0a34dcd7faeb90b1101047d2f09411' 
  AND token = 'iRVg0AGz7xDd4VbFXvKFl5SEwB2YD6i+TuK1cjiRTkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}