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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d876c8d8cfd2fb3a073d461aae30c6a976dbc5ad934b68343398435bb42029' 
  AND token = 'qxg8R6iqO9PvS63YqOJyRn1LzSkA2n5NTCg6EJ2h7e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}