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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435bd7b4bf8276ebb93298d321e7a3b5f6813ccc91fb0881ffe6b648d78f2e2b' 
  AND token = 'b6A4fiCnhLZ4o0vLBLpPb/to72BMQsY9kzLWzrW7Kbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}