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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746eb2572ddbb312579fc6e782809f5f3d6fbaa09cb221d50b25ee03dcd2e78a' 
  AND token = 'PmdKQ6UqpseVBBcucV3BGpP1NEv9o1mtu0yuIYkyLLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}