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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd38820e8e979a92818e67d58570f6632b58f9e5859834fad1d905fc90f49ecd' 
  AND token = 'ARdGRLI80/jh7dvroFgBxutUXgPnBikSF31lBxzmuBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}