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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b046f7b3e8f6345691d539da842fe2f51b47935065db2d65d82b0f8c717baa9' 
  AND token = 'nr/x7VzhjdN1aFNat/rTeO3WfO9/5AIPS1cEz4WKtN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}