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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6defb5bd33c4d3df9e43b95f2d3bbab9e721e438fcaa7a22c8d0c80b8b8c4c6' 
  AND token = 'tMMqIRDPLSOdtb7Bu59hE7g5R3rh+Bf2YbhLKhL+0GE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}