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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3167720dbb71264db0741bb51506b13c765db1c81ec8b4342651903c9d3a3470' 
  AND token = 'aDLNLxtACOhOz/5aOpgl4b/CAffuNItynJ3XAYxdr0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}